ABSTRACT
Much emphasis has been given to the deafness of Ludwig van Beethoven and its potential causes. However, when analyzing several symptoms reported by himself throughout his life in many letters and his final illness, a common etiology emerges. This article reports the medical history of this artist, based on authoritative scientific sources.
Subject(s)
Humans , History, 18th Century , History, 19th Century , Inflammatory Bowel Diseases/history , Deafness/history , Famous Persons , Immune System Diseases/history , Music/history , Inflammatory Bowel Diseases/complications , Deafness/etiology , Germany , Immune System Diseases/etiology , Liver Cirrhosis/historyABSTRACT
Background: Nonspecific colitis is an inflammatory Bowel Disease (IBD) that runs a clinically benign course. Histopathologically it is characterized by superficial mucosal erosions with lymphocytic infiltration in the lamina propria with no granuloma. Aim of this study: is to describe the clinical presentation of Non-Specific Colitis (NSC); and to evaluate its response to 5-aminosalicylic acid (5-ASA) in Sudanese patients. Setting and Design: This study is a prospective cohort. A total of 26 patients presenting with bloody; mucoid diarrhoea; lower abdominal pain or colonic mass were included in the study. Methods and Materials: A total of 26 patients presenting with bloody mucoid diarrhoea; lower abdominal pain with or without colonic mass were included in the study. All patients underwent colonoscopy. Statistical analysis: A descriptive statistical analysis was done using SPSS. Results: 19 () of patients were males and 7 were females with male to female ratio of 3:1. The majority of patients 16 (61.6) had bloody diarrhea while 18 (69.2) opened their bowel 4-6 times a day. The majority 10 (38.8) had rectum and sigmoid involvement. All patients showed a good response to 5-ASA. Conclusions: This study showed that NSC has clinical features that are very much similar to mild UC with a rather good clinical response to oral 5-ASA